Trisha Yearwood Returns to Headline Komen’s Band As One Nashville Concert for the Cure at the Opry House

Trisha Yearwood will once again lend her voice to the fight against breast cancer — a cause that became personal when she lost her mother, Gwendolyn, to the disease in 2011. The country star is set to headline Susan G. Komen’s second annual Band As One Nashville Concert for the Cure on March 22, 2026, as the event moves to a new home at the Grand Ole Opry House.

The inaugural concert brought in more than $700,000 and featured some of Music City’s biggest names. Organizers say this year’s show will build on that momentum with surprise performances, survivor stories, and a night of music aimed at supporting those affected by breast cancer.

“We are thrilled to bring Band As One Nashville to the iconic Opry House and continue working with a variety of passionate and talented artists to raise awareness and funds for breast cancer,” said Joshua Daniel, Komen’s Senior Director of Entertainment Engagement and Events. “Last year’s event was a tremendous success, and we look forward to building on that momentum at one of the most legendary venues in country music.”

For Trisha, the mission remains at the heart of her involvement.

“I am excited to join with Susan G. Komen for another year to uplift the breast cancer community through music,” she said. “My favorite part of this event is spreading love throughout the evening, and I look forward to sharing the stage with other artists who are committed to this noble cause.”

Breast cancer continues to claim about one woman every 12 minutes in the U.S. Experts say access to modern treatments could prevent one-third of those deaths. Funds raised at Band As One will support Komen’s research initiatives and patient care programs designed to make the most effective treatments available to everyone.

Tickets are available at komen.org/bandasone.